Symptoms,causes and treatment of liver failure

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The liver is a vital organ in the human body located in the upper right portion of the abdomen, beneath the diaphragm, and above the stomach. 

It’s one of the largest organs and performs a multitude of essential functions crucial for sustaining life.

Liver failure can occur suddenly (acute liver failure) or gradually over time (chronic liver failure). It’s a serious condition where the liver loses its ability to function properly. Best lab in pune

Here’s an overview of symptoms, causes, and treatments for liver failure:


Early symptoms

  • Fatigue
  • Nausea or loss of appetite
  • Diarrhea or constipation. Best lab in pune
  • Abdominal pain or swelling
  • Jaundice (yellowing of the skin and eyes)
  • Easy bruising or bleeding
  • Swelling in the legs and abdomen
  • Mental confusion or disorientation
  • Sleep disturbances. Best lab in pune

Late-stage symptoms:

  • Severe jaundice
  • Excessive bleeding
  • Coma. Best lab in pune
  • Accumulation of fluid in the abdomen (ascites)
  • Kidney failure


Acute liver failure:

  • Viral hepatitis (such as Hepatitis A, B, or C)
  • Drug-induced liver injury (overdose of acetaminophen, for instance)
  • Severe bacterial or viral infections. Best lab in pune
  • Wilson’s disease (a genetic disorder causing copper buildup in the liver)
  • Autoimmune hepatitis (the immune system attacks the liver)

Chronic liver failure:

  • Chronic alcohol abuse
  • Chronic viral hepatitis
  • Non-alcoholic fatty liver disease. Best lab in pune
  • Cirrhosis (scarring of the liver tissue)
  • Hemochromatosis (excessive iron in the body)
  • Primary biliary cirrhosis or primary sclerosing cholangitis


Acute liver failure:

  • Hospitalization for monitoring and supportive care
  • Treatment of the underlying cause (e.g., antidotes for drug overdose)
  • Liver transplant in severe cases. Best lab in pune

Chronic liver failure:

  • Management of underlying conditions (such as antiviral medications for hepatitis)
  • Lifestyle changes (such as alcohol cessation, dietary changes)
  • Medications to manage symptoms and complications
  • Liver transplant in advanced cases. Best lab in pune

Functions of the Liver:

  • Metabolic Functions: The liver metabolizes carbohydrates, proteins, and fats, converting them into energy and essential nutrients for the body. Best lab in pune
  • Detoxification: It filters and detoxifies chemicals, drugs, and toxins, breaking them down into harmless byproducts that can be excreted.
  • Bile Production: The liver produces bile, a substance crucial for digestion that helps break down fats in the small intestine. Best lab in pune
  • Storage of Nutrients: It stores essential nutrients such as vitamins, minerals, and glycogen (a form of glucose used for energy).
  • Blood Regulation: The liver helps regulate blood clotting by producing clotting factors and removing old or damaged blood cells.
  • Immune Function: It plays a role in the body’s immune system by removing bacteria from the bloodstream. Best lab in pune
  • Production of Proteins: The liver synthesizes important proteins necessary for various bodily functions, including albumin and certain hormones.

The symptoms of liver failure can vary depending on the severity of the condition. Common symptoms include jaundice (yellowing of the skin and eyes), fatigue, loss of appetite, nausea, vomiting, abdominal pain and swelling, confusion or changes in behavior, and easy bruising or bleeding.

When it comes to treatment options for liver failure, it depends on the underlying cause and the extent of liver damage. Best lab in pune

In some cases, lifestyle changes such as abstaining from alcohol or maintaining a healthy diet may be sufficient. However, in more severe cases where there is significant liver damage or complete liver failure, a liver transplant may be necessary.

It’s important to seek medical attention if you experience any symptoms associated with liver failure. Early diagnosis and treatment can greatly improve outcomes and prevent further complications.

Treatment aims to address the underlying cause and manage symptoms. In severe cases where the liver has failed irreversibly, a liver transplant might be the only option for long-term survival. Best lab in pune

Early detection and prompt medical care are crucial in managing liver failure. Regular check-ups, vaccination against hepatitis viruses, maintaining a healthy lifestyle, and avoiding excessive alcohol consumption can help prevent certain causes of liver failure.

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